What kind of characterization data is available on your PDX cancer models?
BarneyOI provides a wide variety of details about each model, including the following:
- Patient characteristics (gender, HLA status and prior treatment – for some specimens, the donor patient’s full treatment history is available)
- Tumor characteristics (disease stage, disease grade, cancer type, cancer subtype, model type, tumor site, model ID)
- Primary/Metastasis, with links to related models
- Tumor engraftment details (sample type, mouse strain, implantation site, tumor growth curves)
- Pharmacology study results
- Histology staining slides
- MRI imaging
- Genomic Analysis (expression levels, mutations, gene fusions copy number variations)
- In vitro pharmacology
Whether your ideal model is naïve or pretreated, primary or metastatic, orthotopic or heterotopic PDX or cell culture, developing clinically relevant models and providing a smarter way to find them is one more way Certis delivers Oncology Intelligence.