Fluorescence Imaging With PDOX

Transgenic fluorescent protein-expressing nude and immunocompetent mice for realtime color-coded imaging of the tumor microenvironment.

Visualization Techniques

The PDOX solution includes fluorescence-based imaging tools that enable visualization of tumor behavior in the mouse models in real-time. PDOX enables visualization of the following:

• Real-time metastasis, tumor growth and progression

• Interactions of cancer cells with stromal cells in the tumor microenvironment, which control cancer cell growth and metastasis

• All types of agents, small molecules, proteins can be evaluated for efficacy in the PDOX model.

Non-invasive fluorescent imaging of of a PDOX pancreatic tumor growing in a mouse pancreas.

Imageable Endpoint Orthotopic Cell Line Tumor Models

Expression of fluorescent protein genes allows real-time in vivo imaging of tumor growth, metastasis, angiogenesis and gene expression. Orthotopic imageable models have been proven to be highly valuable in drug discovery and evaluation on primary and metastatic tumors.

To learn more about Certis Oncology fluorescence imaging, reach out to us at info@certisoncology.com.

PDOX Pre-Clinical Brochure